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  • Modelling excitability-dependent diabetes in zebrafish



    Approaches to isolate and record electrical activity in zebrafish pancreatic islets show us that zebrafish beta cells contain the same KATP channels as mammals and exhibit similar KATP-dependent glucose tolerance, providing a model organism to study insulin secretion and glucose handling.

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    Emfinger et al (2017) Expression and function of ATP-dependent potassium channels in zebrafish islet β-cells Royal Society Open Science, in press.